2.0 c6535b38-c654-42d3-b6f7-196c246e625b *AOS_Endometrium_nodes 50/45Gy 25fx SIB v1 Pelvis Uterus *AOS_Endometrium_nodes 50/45Gy 25fx SIB AOS sample template - to be copied, reviewed, modified as deemed appropriate, and approved by site physicist Summary: 25 fx Endometrium and nodes IMRT to 50/45 Gy References: * RTOG 1203 Trial - "A Randomized Phase III Study of Standard vs. IMRT Pelvic Radiation for Post-Operative Treatment of Endometrial and Cervical Cancer (TIME-C)" * ASTRO Practice Guideline for Endometrial Cancer, Pract Rad Oncol 2023. (ASTRO PGEC) Version 1.5 Created: 11/12/2024 Last updated: 4/18/2025 (PHH) - Adjusted sub-P ordering, corrected OAR labels (Femurs and Rectum) *************************************************************************** Rx: "Adjuvant EBRT should be delivered to a total dose of 4500 to 5040 cGy at 180 to 200 cGy per fraction." - ASTRO PGEC OAR Constraints: See table 5 of ASTRO PGEC, page 52. Structures have been named according to TG 263. 14544 FMA 3.2 Rectum 4280929481 Rectum 15900 FMA 3.2 Urinary bladder 4288990249 Bladder 17558 FMA 3.2 Uterus 4291577897 Uterus 32842 FMA 3.2 Femur head & neck right 4291581481 Femur_R 32843 FMA 3.2 Femur head & neck left 4280929420 Femur_L 9680 FMA 3.2 Spinal canal 4278255615 SpinalCanal 5018 FMA 3.2 Bones 4284623308 Bones 7205 FMA 3.2 Left kidney 4283678964 Kidney_L 7204 FMA 3.2 Right kidney 4278233685 Kidney_R 7213 FMA 3.2 Ovary right 4291070207 Ovary_R 7214 FMA 3.2 Ovary left 4294949340 Ovary_L 323971 FMA 3.2 Set of ovaries 4291569983 Ovaries R-429EC SRT Planning target volume 4285595648 PTV_45 Target2 R-429EB SRT Clinical target volume 5 Body BODY 99VMS_STRUCTCODE 1.0 Body plus other external items -3 ]]> R-429EB SRT Clinical target volume 4280918220 CTV_45 Target4 R-429E0 SRT Gross tumor volume 5 Body BODY 99VMS_STRUCTCODE 1.0 Body plus other external items -3 ]]> R-429EC SRT Planning target volume 4294901760 PTV_50 Target5 R-429EB SRT Clinical target volume 5 Body BODY 99VMS_STRUCTCODE 1.0 Body plus other external items -3 ]]> R-429E0 SRT Gross tumor volume 4286578816 GTV_45 R-429EB SRT Clinical target volume 4280918220 CTV_50 Target6 GTVp 99VMS_STRUCTCODE 1.0 Primary gross tumor volume 5 Body BODY 99VMS_STRUCTCODE 1.0 Body plus other external items -3 ]]> GTVp 99VMS_STRUCTCODE 1.0 Primary gross tumor volume 4285868492 GTV_50 R-FE3B6 SRT Bowel bag 4294934528 Bowel_Bag NormalTissue 99VMS_STRUCTCODE 1.0 Unidentified structure 4286595136 Bowel_Bag-CTV ControlRegion1 R-FE3B6 SRT Bowel bag Target5 R-429EB SRT Clinical target volume Body BODY 99VMS_STRUCTCODE 1.0 Body plus other external items -3 ]]> NormalTissue 99VMS_STRUCTCODE 1.0 Unidentified structure 4294902015 Uterus - CTV Target1 1.8 DoseVolume ShouldBeMore 97 Relative 43.65 Absolute DoseVolume ShouldBeMoreOrEqual 97 Relative 40.5 Absolute 2 1 DoseVolume ShouldBeMoreOrEqual 95 Relative 45 Absolute DoseVolume ShouldBeMoreOrEqual 95 Relative 43.65 Absolute 1 2 VolumeDose ShouldBeMoreOrEqual 90 Relative 44.5 Absolute VolumeDose ShouldBeMoreOrEqual 80 Relative 44.5 Absolute VolumeDose ShouldBeLessOrEqual 15 Relative 47.25 Absolute VolumeDose ShouldBeLessOrEqual 50 Relative 47.25 Absolute DoseVolume ShouldBeLessOrEqual 0.03 Absolute 53.5 Absolute DoseVolume ShouldBeLessOrEqual 0.03 Absolute 55 Absolute 2 5 Target3 2 DoseVolume ShouldBeMoreOrEqual 95 Relative 49.99999999999999 Absolute DoseVolume ShouldBeMoreOrEqual 95 Relative 48.5 Absolute 1 3 DoseVolume ShouldBeMoreOrEqual 97 Relative 48.5 Absolute DoseVolume ShouldBeMoreOrEqual 97 Relative 44.99999999999999 Absolute 2 2 DoseVolume ShouldBeLessOrEqual 0.03 Absolute 53.5 Absolute DoseVolume ShouldBeLessOrEqual 0.03 Absolute 54.99999999999999 Absolute 2 6 OAR1 VolumeDose ShouldBeLess 80 Relative 40 Absolute VolumeDose ShouldBeLessOrEqual 90 Relative 40 Absolute 3 1 OAR1 MeanDose OAR2 VolumeDose ShouldBeLessOrEqual 35 Relative 45 Absolute 2 3 OAR2 MeanDose OAR4 DoseVolume ShouldBeLessOrEqual 0.03 Absolute 50 Absolute DoseVolume ShouldBeLessOrEqual 0.03 Absolute 55 Absolute 3 3 OAR5 DoseVolume ShouldBeLessOrEqual 0.03 Absolute 50 Absolute DoseVolume ShouldBeLessOrEqual 0.03 Absolute 55 Absolute 3 4 OAR6 DoseVolume ShouldBeLessOrEqual 0.03 Absolute 45 Absolute DoseVolume ShouldBeLessOrEqual 0.03 Absolute 47.5 Absolute 1 1 OAR8 MeanDose ShouldBeLess 10 Absolute MeanDose ShouldBeLessOrEqual 15 Absolute 4 1 OAR9 MeanDose ShouldBeLess 10 Absolute MeanDose ShouldBeLessOrEqual 15 Absolute 4 2 ControlRegion1 VolumeDose ShouldBeLessOrEqual 30 Relative 40 Absolute 3 2 ControlRegion1 MeanDose ControlRegion2 VolumeDose ShouldBeLessOrEqual 30 Relative 40 Absolute 2 4 ControlRegion2 MeanDose OAR7 VolumeDose ShouldBeLessOrEqual 37 Relative 40 Absolute VolumeDose ShouldBeLessOrEqual 60 Relative 40 Absolute 2 7 OAR7 VolumeDose ShouldBeLessOrEqual 90 Relative 10 Absolute 3 5 OAR7 VolumeDose ShouldBeLessOrEqual 90 Relative 25 Absolute 3 6 OAR11 VolumeDose ShouldBeLessOrEqual 30 Relative 50 Absolute 3 7 OAR10 VolumeDose ShouldBeLessOrEqual 30 Relative 50 Absolute 3 8 NoNormalization 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None 1 None